Chronic Wasting Disease (CWD) has been an ongoing case amongst cervids and other organisms affecting them neurologically, causing brain degeneration, weight loss, behavioral problems, and death. This threatens the wildlife population, affecting population dynamics and poses a risk to the health of our ecosystem. In order to implement regulations in response to these detections and preventions protocol, we’ve partnered up with the California Department of Fish and Wildlife to improve on their CWD sampling process for a more compact sampling workflow prototype that reduces cross-contamination, minimizes waste, and improve efficiency in CWD lymph node processing. We aim to implement a new design incorporating accessible and low cost equipment while ensuring the use of PPE.